The adjuvant therapeutic effect of ozone therapy on cancer


In 1980, an article was published in Science stating that "ozone can selectively inhibit the growth of human lung, breast, and uterine cancer cells in vitro, and the percentage of cancer cells killed by ozone is related to ozone concentration and dosage". In the article, human lung diploid fibroblasts were used as control cells. When the ozone concentration in the environment was 0.3ppm and 0.5ppm, the percentage of inhibition of cancer cell growth by ozone was 40% and 60%, respectively, while no effect was found on the control cells. When the ozone concentration is 0.8ppm, the percentage of cancer cell growth inhibition exceeds 90%, while the growth inhibition rate of control cells is less than 50%. It is evident that the human body's defense mechanism against ozone damage reduces the number of human cancer cells.

Cancer cells are significantly sensitive to ozone. By increasing the concentration of ozone, it was found that all major components of normal cells were affected. Reduced glutathione (GSH) inactivates peroxides and free radicals by contributing one hydrogen atom to ozone. These findings suggest that the use of ozone alone, or in combination with radiotherapy, or the use of electrophilic compounds in chemotherapy, may have adjuvant therapeutic value for certain forms of lung cancer patients.

In the 1990s, Professor Bocci from Italy theoretically studied the immunomodulatory effects of ozone therapy on the human body through in vivo experiments. Lower concentrations and doses of ozone can activate immune active cells and release immune factors. Compared with atmospheric ozone therapy, high-pressure ozone therapy not only has the advantages of atmospheric ozone therapy, but also significantly increases blood oxygen partial pressure, improves arterial blood oxygen saturation, and improves oxygen distribution in tissues.

Dr. Horst Kief from Germany administered four months of high-pressure ozone therapy to patients with skin cancer, lymphoma, sarcoma, and kidney tumors who had been unresponsive to long-term chemotherapy and radiation therapy. The results showed that the patient's levels of interferon gamma increased by 7-9 times. The patient feels that their symptoms have improved. In addition, there are reports abroad of the positive effects of high-pressure ozone therapy on patients with advanced head and neck tumors, as well as the improvement of oxygenation in hypoxic tumors.

High pressure ozone therapy, as one of the adjuvant treatment methods for cancer patients, aims to prolong or maintain the therapeutic effect, improve the health status and lifestyle of patients, and enhance their quality of life. Although the introduction of German biological oxidation therapy and ozone therapy to China has not been long, as an adjuvant treatment method available for cancer patients to choose from, scientific research and clinical practice for medical workers in China may have positive significance.





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