Application of ozone in burn department

Indications: burns (difficult to heal wounds), skin injuries, etc.

Ozone therapy for wounds that are difficult to heal
After infection, the healing time of the wound is prolonged. If the inflammation develops severely, it can cause extensive ulceration of the wound and even pose a risk of sepsis. Ozone is highly efficient in killing bacteria, dilating blood vessels, improving blood flow, reducing edema near nerve roots, and improving microcirculation; This accelerates the healing of the wound.
Ozone fumigation treatment can stimulate the overexpression of oxidase, neutralize the excessive production of reactive oxidative products in inflammatory reactions, antagonize the release of immune factors in inflammatory reactions, dilate blood vessels, improve blood flow, and reduce edema near nerve roots; At the same time, ozone, as a strong oxidant, has bactericidal and antiviral effects. Ozone can react with lipid double bonds in bacterial cell walls, penetrate into the interior of bacterial cells, act on lipoproteins and lipopolysaccharides, change cell permeability, and lead to bacterial dissolution and death; It can also destroy the four polypeptide chains of the viral coat protein and damage its DNA. Thus, it plays a direct role in clearing invading wound fungi.
This method has a good effect on treating non healing wounds, especially for patients with simple traumatic wound infections. Generally, after 2-3 fumigations, the wound will scab and basically recover. 85.7% of patients recover, and the total effective rate is 100%.

Ozone therapy for skin injuries, burns, and scalds
Ozone is currently known as the strongest bactericidal agent, with a bactericidal ability 1000 times that of chloride ions, 4000 times that of ultraviolet radiation, tens of thousands of times that of antibiotics and traditional Chinese medicine. Ozone is still a strong green oxidant, and virus inactivation is achieved by directly destroying its ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) substances. For bacteria, fungi, and fungal microorganisms, they first act on the cell membrane, causing damage to the membrane components, leading to metabolic disorders and inhibiting their growth. Then, they inherit and infiltrate to destroy the tissue inside the membrane and kill it.

Ozone is currently widely used in skin injuries (bacteria), burns, scalds (bacteria), etc.
Ozone water therapy is to use ozone water formed after mixing double distilled water and ozone gas to wash the ulcer surface, while ozone limb bag therapy is to directly use mixed gas to fumigate the diseased parts. Both methods have comparative effects on bedsores, diabetes gangrene, burns, refractory injuries, surgical wounds, etc. Its mechanism of action is that ozone has a high degree of oxidizing ability and has a killing effect on bacteria, fungi, and viruses.

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