The mechanism of ozone therapy for intervertebral discs


Intervertebral ozone injection is the most advanced minimally invasive treatment technique for treating intervertebral disc herniation in recent years. This therapy was first pioneered by Italian physicians and is currently widely used in some European countries such as Italy, Germany, and France. It has been confirmed to be the most effective means of treating lumbar protrusion without surgery.

Folding principle
The principle of lumbar intervertebral disc O3 injection is that high concentration O3 has strong oxidative ability, as well as anti-inflammatory and analgesic effects. Injecting it into the protruding nucleus pulposus tissue of the intervertebral disc can instantly oxidize the proteoglycans in the nucleus pulposus tissue and destroy the nucleus pulposus cells, causing the loss of proteoglycan function, reducing the production of proteoglycans by cells, and the osmotic pressure of the nucleus pulposus tissue cannot be maintained, resulting in water loss and atrophy, thereby reducing the pressure inside the intervertebral disc and eliminating symptoms, achieving the goal of treatment.

Folding application scope
Which patients with lumbar protrusion are suitable for O3 injection surgery:

1. Patients with bulging and mild to moderate protrusion combined with root compression symptoms.

2. Clinical symptoms are obvious, including persistent lower back and leg pain, claudication, etc.

3. Positive signs of spinal nerve compression or abnormal skin sensation, such as positive results in straight leg elevation test.

4. Diagnosed with inclusive or simple disc herniation or bulging through imaging examinations such as CT or magnetic resonance imaging, and the imaging findings are consistent with clinical symptoms and signs.

Conservative treatment for more than four weeks has poor results.

6. Surgical treatment or other minimally invasive treatments for intervertebral discs have poor results.

7. Low back pain that has been treated conservatively but has not been cured for a long time, without obvious symptoms of nerve compression, but has been confirmed by imaging to have flat intervertebral disc lesions, such as disc herniation, and other causes have been ruled out.

Which patients with lumbar protrusion are not suitable for O3 injection surgery

1. Significant narrowing of the lumbar intervertebral disc indicates severe degenerative changes.

2. Merge spinal stenosis and lateral recess stenosis.

3. Calcification of lumbar disc herniation.

4. Long history of lumbar disc herniation.

5. CT or MRI shows obvious adhesion of the protruding medullary column.

6. Combined with cauda equina compression syndrome, such as urinary and fecal dysfunction.

7. Combined vertebral slippage.

8. There is a bleeding disorder.

9. Merge spinal canal or other spinal diseases, such as spinal canal tumors, vertebral displacement tumors, etc.

10. Individuals with severe liver and kidney dysfunction.

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Folding advantages
The main advantages of ozone injection therapy for treating lumbar protrusion are:

1. High safety factor, fine needle puncture under local anesthesia, mainly targeting the nucleus pulposus, without affecting other tissues;

Minimally invasive treatment has lower risks, is more effective than conservative treatment, and eliminates the pain of surgery;

Accurate positioning. Accurate guidance and positioning under CT machine without deviation;

Rapid onset and high therapeutic effect. To cure the stubborn condition of lumbar protrusion, usually only one injection is needed, and the effect is fast;

There were no significant postoperative complications. Ozone itself has a disinfectant effect, greatly reducing the chance of infection.

It can cause prominent spinal atrophy and eliminate aseptic inflammation of nerve roots.






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