1、 Overview
Ozone (O3) is an isomer of oxygen, a molecule composed of three oxygen atoms. It is colored, odorous, highly specific, easily differentiated, soluble in water, and has a half-life of about 20 minutes. The molecular structure of ozone is very unstable, and it quickly differentiates into oxygen (O2) and a single oxygen atom (O) at room temperature. The single oxygen atom (O) has strong activity and is a strong oxidant. It can oxygenate bacteria, viruses and other microorganisms and some arranged cells of the human body, improve blood oxygen saturation, improve the body arrangement, and influence the proliferation of white blood cells. Therefore, it is widely used in many European and American countries for the treatment or auxiliary treatment of bacterial and viral infections, peripheral and cerebral artery circulation obstruction, arthritis, skin injuries, tumors, AIDS, herniation of intervertebral discs and other diseases.

The clinical treatment of intervertebral disc herniation using ozone began in the 1980s. In 1988, Italian physician Verga was the first to inject ozone gas mixture into the vertebrae to treat outstanding lumbar and leg pain caused by intervertebral discs, achieving satisfactory results. Subsequently, many experts in France and Germany conducted research on its use and achieved outstanding clinical results. Professor He Xiaofeng from Guangzhou Nanfang Hospital first introduced this skill to China and promoted it in 2000. As clinical use becomes increasingly widespread, skills become more sophisticated, experiences become richer, and efficiency continues to improve. If the concentration of the mixed gas is written, it was initially 27ug/L, and later gradually added, with a selection of 45-55ug/L. The amount of ozone mixed gas written was initially 10-15 ml per intervertebral disc, but later domestic experts such as He Qing wrote over 90 ml per intervertebral disc, and the excellent rate also improved to 87% 9%. Several hospitals have now implemented this skill, making ozone gas injection a common method for interventional treatment of intervertebral disc herniation.

2、 Principle
Because ozone has a strong oxidizing effect, after being written into the intervertebral disc, it can quickly oxidize the primary matrix of the nucleus pulposus - polysaccharide protein aggregates, causing a decrease in osmotic pressure and depolymerization, resulting in the loss of many water molecules, causing the nucleus pulposus to dry up and denature, shrink in volume, and shrink back, achieving the intention of reducing nerve root compression. The relief of nerve root pressure can improve the damage to the nerve membrane and pathological changes such as microcirculation obstruction, edema, and hypoxia caused by compression.
Ozone can inhibit the synthesis of pro-inflammatory prostaglandins, antagonize aseptic inflammation caused by the immune response of the body to substances such as glycoproteins and beta proteins released after the rupture of the fibrous ring around nerve roots, improve microcirculation, add oxygen supply, alleviate nerve root edema and adhesion, and achieve the intention of reducing pain. Ozone can neutralize or inhibit the activity of chemical substances such as phosphatase A2 in the nucleus pulposus arrangement, alleviate or eliminate their inflammatory effects on nerve roots, and achieve the intention of relieving pain.
The research results have confirmed that ozone has the effects of nerve root decompression, anti-inflammatory, and analgesic in the treatment of intervertebral disc herniation. However, the specific mechanism of its effect is not yet fully understood and needs further research.

3、 Habitual certificate selection
1. Clinical symptoms of intervertebral disc herniation or prominent compression of nerve roots that are consistent with imaging examinations, and conservative treatment is ineffective.
2. Intervertebral disc herniation, but mild in severity, with intact posterior longitudinal ligament and not yet free.

4、 Taboo certificate
1. Impressionology examination shows intervertebral disc herniation;
2. Outstanding intervertebral disc combined with narrow intervertebral space;
3. Outstanding intervertebral disc with vertebral body slippage of grade I or above;
4. Outstanding intervertebral disc with significant calcification;
5. Patients with acquired infections, tumors, and severe systemic diseases.



More content:Carnoy  www.kzyyl.com